טמפרטורה: חמימה.

לחות: נייטראלית.

טעם: מתקתק.

מרידיאנים: ריאות, כליות.

תמצית נוזלית (טינקטורה): בריכוז של 1:3, 45% אלכוהול, 6-18 מ”ל ליום.

תמצית יבשה: תמצית תקנית 30:1 בריכוז של 10% פוליסכרידים, 300-2,000 מ”ג ליום.

מרתח: 2-5 גרם ליום.

כחלק מפורמולה: 20-30%.

פוליסכרידים:

Exopolysaccharide fraction (EPSF)

Acid polysaccharide (APS)

Polysaccharide CS-F30

Polysaccharide CS-F10

Polysaccharide CPS-1

Polysaccharide CPS-2

polysaccharide CME-1

Polysaccharide CS-F10

Cordyglucans

Cordysinocan

מונוסכרידים:

Rhamnose

Ribose

Arabinose

Xylose

Mannose

Glucose

Galactose

Fructose

Sorbose

Mannitol

Cordyceptic acid

Monosaccharide saponins

סטרולים:

Ergosterol

H1-A

glycoside derivatives of sterols

נוקלאוזידים:

Cordycepin

3’-deoxyadenosine

פוליאמינים:

spermine

Spermidine

Putrescine

1,3-diaminopropane

נוקליאוטידים:

uridine

Adenosine

Guanosine

ויטמינים:

ויטמינים ממשפחת B-complex

מינרלים:

אשלגן (Potassium)

גופרית (Sulfur)

זרחן (Phosphorus)

סידן (Calcium)

מגנזיום (Magnesium)

מנגן (Manganese)

ברזל (Iron)

בריום (Barium)

כרום (Chromium)

בורון (Boron)

אבץ (Zinc)

נחושת (Copper)

סטרונציום (Strontium)

חומצות שומן:

Oleic acid

Linoleic acid

Palmitic acid

Stearic acid

Docostatetraenoic acid

Lignoceric acid

Myristic acid

Behenic acid

חומצות אמינו:

Tryptophan

Cysteic acid

Aspartic acid

Methionine

Threonine

Serine

Glutamic acid

Proline

Glycine

Alanine

Valine

Isoleucine

Leucine

Tyrosine

Phenylalanine

Lysine

Histidine

arginine

חלבונים יחודיים:

Proteases

CSDNase

Serine Protease CSP

Cordymin

Cordycedipeptide A

Cordyceamides A,B

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5 Li SP, Zhang GH, Zeng Q, Huang ZG, Wang YT, Dong TT, Tsim KW. Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia. Phytomedicine, 13(6), 2006, 428–433.

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13 HJ Cho, JY Cho, MH Rhee, HJ Park. Cordycepin (3′-deoxyadenosine) inhibits human platelet aggregation in a cyclic AMP-and cyclic GMP-dependent manner. European journal of pharmacology, 2007.

14 Tsai YJ, Lin LC, Tsai TH. Pharmacokinetics of adenosine and cordycepin, a bioactive constituent of Cordyceps sinensis in rat. J Agric Food Chem. 2010 Apr 28;58(8):4638-43. doi: 10.1021/jf100269g.

15 Yu HM, Wang BS, Huang SC, Duh PD. Comparison of protective effects between cultured Cordyceps militaris and natural Cordyceps sinensis against oxidative damage. J Agric Food Chem. 2006 Apr 19;54(8):3132-8.

16 Yue GG, Lau CB, Fung KP, Leung PC, Ko WH. Effects of Cordyceps sinensis, Cordyceps militaris and their isolated compounds on ion transport in Calu-3 human airway epithelial cells. J Ethnopharmacol. 2008 Apr 17;117(1):92-101. doi: 10.1016/j.jep.2008.01.030. Epub 2008 Feb 6.

17 Guan J, Zhao J, Feng K, Hu DJ, Li SP. Comparison and characterization of polysaccharides from natural and cultured Cordyceps using saccharide mapping. Anal Bioanal Chem. 2011 Apr;399(10):3465-74. doi: 10.1007/s00216-010-4396-y. Epub 2010 Dec 9.

18 Li SP, Yang FQ, Tsim KW. Quality control of Cordyceps sinensis, a valued traditional Chinese medicine. J Pharm Biomed Anal. 2006 Aug 28;41(5):1571-84. Epub 2006 Feb 28.

19 Yu L, Zhao J, Li SP, Fan H, Hong M, Wang YT, Zhu Q. Quality evaluation of Cordyceps through simultaneous determination of eleven nucleosides and bases by RP-HPLC. J Sep Sci. 2006 May;29(7):953-8.

20 Zhou X, Luo L, Dressel W, Shadier G, Krumbiegel D, Schmidtke P, Zepp F, Meyer CU. Cordycepin is an immunoregulatory active ingredient of Cordyceps sinensis. Am J Chin Med. 2008;36(5):967-80.

21 Wang Z, Li N, Wang M, Wang Y, Du L, Ji X, Yu A, Zhang H, Qiu F. Simultaneous determination of nucleosides and their bases in Cordyceps sinensis and its substitutes by matrix solid-phase dispersion extraction and HPLC. J Sep Sci. 2013 Jul;36(14):2348-57. doi: 10.1002/jssc.201300204. Epub 2013 Jun 21.

22 Zhang L, Dai X, Xu F, Wang F, Gong B, Wei Y. Preparation of imidazole-functionalized silica by surface-initiated atom transfer radical polymerization and its application for hydrophilic interaction chromatography. Anal Bioanal Chem. 2012 Sep;404(5):1477-84. doi: 10.1007/s00216-012-6210-5. Epub 2012 Jul 8.

23 Gong YX, Li SP, Li P, Liu JJ, Wang YT. Simultaneous determination of six main nucleosides and bases in natural and cultured Cordyceps by capillary electrophoresis. J Chromatogr A. 2004 Nov 5;1055(1-2):215-21.

24 Yang FQ, Li DQ, Feng K, Hu DJ, Li SP. Determination of nucleotides, nucleosides and their transformation products in Cordyceps by ion-pairing reversed-phase liquid chromatography-mass spectrometry. J Chromatogr A. 2010 Aug 20;1217(34):5501-10. doi: 10.1016/j.chroma.2010.06.062. Epub 2010 Jun 30.

25 Zhao HQ, Wang X, Li HM, Yang B, Yang HJ, Huang L. Characterization of nucleosides and nucleobases in natural Cordyceps by HILIC-ESI/TOF/MS and HILIC-ESI/MS. Molecules. 2013 Aug 15;18(8):9755-69. doi: 10.3390/molecules18089755.

26 Yang FQ, Ge L, Yong JW, Tan SN, Li SP. Determination of nucleosides and nucleobases in different species of Cordyceps by capillary electrophoresis-mass spectrometry. J Pharm Biomed Anal. 2009 Oct 15;50(3):307-14. doi: 10.1016/j.jpba.2009.04.027. Epub 2009 May 5.

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29 Jia JM, Ma XC, Wu CF, Wu LJ, Hu GS. Cordycedipeptide A, a new cyclodipeptide from the culture liquid of Cordyceps sinensis (Berk.) Sacc. Chem Pharm Bull (Tokyo). 2005 May;53(5):582-3.

30 Rukachaisirikul V, Chantaruk S, Tansakul C, Saithong S, Chaicharernwimonkoon L, Pakawatchai C, Isaka M, Intereya K. A cyclopeptide from the Insect pathogenic fungus Cordyceps sp. BCC 1788. J Nat Prod. 2006 Feb;69(2):305-7.

31 Zhang Y, Liu S, Liu H, Liu X, Che Y. Cycloaspeptides F and G, Cyclic Pentapeptides from a Cordyceps-colonizing isolate of Isaria farinosa. J Nat Prod. 2009 Jul;72(7):1364-7. doi: 10.1021/np900205m.

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33 TH Hsu, LH Shiao, C Hsieh, DM Chang. A comparison of the chemical composition and bioactive ingredients of the Chinese medicinal mushroom DongChongXiaCao, its counterfeit and mimic, and fermented mycelium of Cordyceps sinensis. Food chemistry, 2002.